"If there's a silence in a room I'll try to fill it as soon as humanly possible."

"Vicodin, I got addicted to that little pill. The reason I don't talk about it too much in the press is because it isn't funny, and I love to be funny in interviews. If you joke about that period in your life, it doesn't seem right."

"Chandler's the guy everybody thinks will do well with women, but he thinks too much and says the wrong thing."

"I love the idea of "the one" but I actually believe that there isn't a Miss Right. There are 12,000 Miss Rights out there and it's all timing."

"I would like you all to give me a round of applause as I have not crashed my car in over 15 months."

"The goal is to have to do the shot again because the camera guy shook a little bit as he was laughing. Without that happening, I'm not happy because there's nothing better for me than a world that everybody's just trying to make each other laugh."

"Well, I was lucky enough to be involved in about 19 failures at an early age, so I'm realistic about the success I'm having and how quickly it can go away. What's important is to be smart about it."

"Ninety percent of video game AI really is pretty damn bad. I think that's actually why it's so much fun to shoot things. Because the AI is so bad and the characters are so annoying."

"I can tell if someone is talking to me because I'm on "Friends" or cause they just think I'm neat. You know I don't think I've ever spent more than five or ten minutes with somebody who was ogling me because they recognized me from the show."

"I'm a sensitive guy. If you are a woman and you're in any kind of emotional duress and you write a song about it, I'll buy you album."

"I've just found out there are pages on the internet dedicated to whether I'm gay or not."

"As an actor, being on autopilot is the worst thing possible."

"After I got my first laugh on stage, I was hooked."

"There are two ways to go when you hit that crossroads in your life: There is the bad way, when you sort of give up, and then there is the really hard way, when you fight back. I went the hard way and came out of it okay. Now, I'm sitting here and doing great."

"I used to be a real prince charming if I went on a date with a girl. But then I'd get to where I was likely to have a stroke from the stress of keeping up my act. I've since learned the key to a good date is to pay attention on her."

"The key to sitcom success is miserable people. If you see a happy couple, it's just gone, like when Sam and Diane got together on Cheers."