"Having been let out of the barn once, I know I wouldn't be happy if I were home all the time."

"I want to feel my life while I'm in it."

"If I am not confident that I can portray the character perfectly on screen, I won't even try."

"Every single decision I make about what material I do, what I'm putting out in the world, is because of my children."

"The more you are in this business, the more humbled by it you become."

"I have a holistic need to work and to have huge ties of love in my life. I can't imagine eschewing one for the other."

"There are improbable things suspended in space, like the earth."

"The progression of roles you take strings together a portrait of an actor, but it's a completely random process."

"I couldn't care less about fashion. If I had taken any clothes home, they would have remained in my closet for the rest of their existence."

"We are who we're going to be when we're very old, and when we're very old we are who we were when we were 8."

"My job is usually to express emotion as freely as possible."

"All that attention to the perfect lighting, the perfect this, the perfect that, I find terribly annoying."

"I think the most liberating thing I did early on was to free myself from any concern with my looks as they pertained to my work."

"The reason I chose the movies that I did was based on where they were being filmed."

"The great gift of human beings is that we have the power of empathy."

"Everything we say signifies; everything counts, that we put out into the world. It impacts on kids, it impacts on the zeitgeist of the time."

"My family really does come first. It always did and always will."

"My feeling about fears is, if you voice your fears, they may come true. I'm superstitious enough to believe that."

"The work is the most fun; it seems illicit how much fun it is."

"I need to go where people are serious about acting."

"I have four to five months, tops, per year to give to my acting work."

"How you first meet the public is how the industry sees you. You can't argue with them. That's their perception."

"I think your self emerges more clearly over time."

"The work will stand, no matter what."

"Expensive clothes are a waste of money."

"Some people are filled by compassion and a desire to do good, and some simply don't think anything's going to make a difference."

"Integrate what you believe in every single area of your life. Take your heart to work and ask the most and best of everybody else, too."

"For me, clothes are kind of character; I don't follow fashion or understand trends."

"It's bizarre that the produce manager is more important to my children's health than the pediatrician."

"There's no road map on how to raise a family: it's always an enormous negotiation."

"I have a very good life - I'm lucky enough not to be deprived."

"I don't like to be gone all weekend and at night too. Because for 20 years, I've had children who are in school."

"America doesn't reward people of my age, either in day-to-day life or for their performances."

"It is well that the earth is round that we do not see too far ahead."

"I'm curious about other people. That's the essence of my acting. I'm interested in what it would be like to be you."

"I believe in imagination. I did Kramer vs. Kramer before I had children. But the mother I would be was already inside me."

"Motherhood has a very humanizing effect. Everything gets reduced to essentials."

"All an actor has is their blind faith that they are who they say they are today, in any scene."

"I don't know why I don't watch a lot of movies; I can barely keep up with the things my friends are in. There isn't enough time in life."

"Sometimes with my children, I remember exactly how I felt as the child in this situation, not just how it feels to be me."

"The interesting thing about being a mother is that everyone wants pets, but no one but me cleans the kitty litter."

"Interestingly, young people don't come to you for advice. Especially the ones who are related to you."

"Personality is immediately apparent, from birth, and I don't think it really changes."

"You just have to keep on doing what you do. It's the lesson I get from my husband; he just says, Keep going. Start by starting."

"Acting is not about being someone different. It's finding the similarity in what is apparently different, then finding myself in there."

"Chris Cooper is one of my favorite actors in the world. I've seen him in most everything he's done."

"Obsession is an attractive thing. People who are really, really interested and good at one thing and smart are attractive, if they're men."

"Enough people write about me every day without even interviewing me."

"I'm a pain in the ass to all of the costume designers with whom I work because I have very strong feelings about the subject."

"I had this sort of idolatry for certain actors who preceded me, people who inspired me, so I'm honored to be that way for young actors."