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"When I write, I aim in my mind not toward New York but toward a vague spot a little to the east of Kansas."
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"The mind is an instrument made up of universal consciousness, egocentric consciousness, societal consciousness, along with education, values, virtues, judgment and wisdom."

"If you want to understand the inner workings of the human mind, read good fiction."

"When you say to someone "follow your heart, it actually refers to the rhetorical representation of various emotions, that are precisely produced from neural activity of the limbic system. So, the metaphoric heart we always boast about while giving advice to our friends, is actually not anywhere near the biological organ known as heart. Rather it too, like all other elements of the human mind exists only in the brain."

"All endeavors, heroic or monstrous, scientific or philosophical, rise from the electrochemical functioning of the mind, that takes place relentlessly in the little specks of protoplasm inside the head. These specks of jelly inside the brain, known as the neurons, determine our identity, personality and everything that we are."

"People always talk like there's a bright line between imagination and memory, but there isn't, at least not for me. I remember what I've imagined and imagine what I remember."

"Thoughts are supreme. It is driving the car we call life. So to reach the deserved destination think right."

"Your skull encloses your brains. But never forget that anytime you open your mouth to talk, you have opened your mind for the entire world to see what is hidden in there!"
Explore more quotes by John Updike

"Existence itself does not feel horrible; it feels like an ecstasy, rather, which we have only to be still to experience."

"Women, fire in their crotch, won't burn out, begin by fighting off pricks, end by going wild hunting for one that still works."

"The fullness ends when we give Nature her ransom, when we make children for her. Then she is through with us, and we become, first inside, and then outside, junk. Flower stalks."

"The refusal to rest content, the willingness to risk excess on behalf of one's obsessions, is what distinguishes artists from entertainers, and what makes some artists adventurers on behalf of us all."

"Customs and convictions change; respectable people are the last to know, or to admit, the change, and the ones most offended by fresh reflections of the facts in the mirror of art."

"To guarantee the individual maximum freedom within a social frame of minimal laws ensures - if not happiness - its hopeful pursuit."
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