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Charles Nicole

"Of all the problems which were open to me for study, typhus was the most urgent and the most unexplored. We knew nothing of the way in which contagion spread."

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"Of all the problems which were open to me for study, typhus was the most urgent and the most unexplored. We knew nothing of the way in which contagion spread."

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Donna Grant

"Since philosophy now criticizes everything it comes across, a critique of philosophy would be nothing less than a just reprisal."

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Personal Development

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Donna Grant

"Nothing is so firmly believed as what we least know."

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Personal Development

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Donna Grant

"He is poor indeed that can promise nothing."

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Donna Grant

"Thou hast seen nothing yet."

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Donna Grant

"If the world were good for nothing else, it is a fine subject for speculation."

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Donna Grant

"Human beings are so made that the ones who do the crushing feel nothing; it is the person crushed who feels what is happening. Unless one has placed oneself on the side of the oppressed, to feel with them, one cannot understand."

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Donna Grant

"I see that all of us who live are nothing but images or insubstantial shadow."

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Donna Grant

"I see the state of all of us who live, nothing more than phantoms or a weightless shadow."

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Donna Grant

"The universal order and the personal order are nothing but different expressions and manifestations of a common underlying principle."

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Donna Grant

"Nothing matters but the writing. There has been nothing else worthwhile... a stain upon the silence."

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Charles Nicole
"Just as the only reservoir for the typhus virus in nature is provided by man, so the only vector of infection is the louse. The bite of the louse is not virulent immediately after the infecting meal. It becomes so only towards the 7th day following infection."

Nature

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Charles Nicole
"At the time when I was conducting my research there was no known method for taking the guinea pig's temperature. I demonstrated a technique which is now widely used."

Time

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Charles Nicole
"Most of the doctors in the Tunisian administration, especially those in country districts, contracted typhus and approximately one third of them died of it."

Country

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Charles Nicole
"I demonstrated the characteristics of experimental fever. It appears after an incubation period which is never less than five days. It follows the same pattern as natural fever in man, but is of shorter duration and less pronounced."

Man

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Charles Nicole
"The discovery that I soon made that the guinea pig was also susceptible to infection made it possible for me, from the third year on, to preserve the virus on this animal."

Discovery

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Charles Nicole
"Of all the problems which were open to me for study, typhus was the most urgent and the most unexplored. We knew nothing of the way in which contagion spread."

Nothing

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Charles Nicole
"From the practical point of view, the susceptibility to infection of the guinea pig proved to be the most useful step forward. Today, all laboratories use this animal for preserving the virus."

Today

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Charles Nicole
"It did not seem likely that I was destined to undertake research on typhus."

Research

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Charles Nicole
"My first attempts to transmit typhus to laboratory animals, including the smaller species of monkeys, had failed, as had those of my predecessors, for reasons which I can easily supply today."

Animals

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Charles Nicole
"I was less successful in my attempts to effect preventive vaccination against typhus by using the virus and in trying to produce large quantities of serum using large animals."

Success

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