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Francis Crick

"Do codons overlap? In other words, as we read along the genetic message do we find a base which is a member of two or more codons? It now seems fairly certain that codons do not overlap."

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"Do codons overlap? In other words, as we read along the genetic message do we find a base which is a member of two or more codons? It now seems fairly certain that codons do not overlap."

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Akiroq Brost

"I have a role now that I think becomes me. I am a grandmother."

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Akiroq Brost

"We have our own reasons for what's motivating us right now."

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Akiroq Brost

"If matters go badly now, they will not always be so."

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Akiroq Brost

"Roused by the lash of his own stubborn tail our lion now will foreign foes assail."

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Akiroq Brost

"If you're not failing every now and again, it's a sign you're not doing anything very innovative."

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Akiroq Brost

"The Bermuda Triangle got tired of warm weather. It moved to Alaska. Now Santa Claus is missing."

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Akiroq Brost

"I think now that the great thing is not so much the formulation of an answer for myself, for the theater, or the play-but rather the most accurate possible statement of the problem."

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Akiroq Brost

"I was in a queer mood, thinking myself very old: but now I am a woman again - as I always am when I write."

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Akiroq Brost

"Ask yourself: was there anything I could have done to prevent the situation? If the answer is yes, do something now and become a better person for it."

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Akiroq Brost

"The slapdash way producers used to assemble a show seems a little unbelievable when we talk about them now."

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Francis Crick
"A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here."

Ideas

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Francis Crick
"If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place."

Example

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Francis Crick
"Attempts have been made from a study of the changes produced by mutation to obtain the relative order of the bases within various triplets, but my own view is that these are premature until there is more extensive and more reliable data on the composition of the triplets."

Order

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Francis Crick
"It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code."

Nature

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Francis Crick
"It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid."

May

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Francis Crick
"It seems likely that most if not all the genetic information in any organism is carried by nucleic acid - usually by DNA, although certain small viruses use RNA as their genetic material."

Information

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Francis Crick
"We are sometimes asked what the result would be if we put four +'s in one gene. To answer this my colleagues have recently put together not merely four but six +'s."

Result

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Francis Crick
"The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code more than one amino acid. However one would certainly expect such triplets to be in a minority."

Possibility

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Francis Crick
"It is one of the more striking generalizations of biochemistry - which surprisingly is hardly ever mentioned in the biochemical textbooks - that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature."

Nature

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Francis Crick
"A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement."

Agreement

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