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Francis Crick

"We are sometimes asked what the result would be if we put four +'s in one gene. To answer this my colleagues have recently put together not merely four but six +'s."

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"We are sometimes asked what the result would be if we put four +'s in one gene. To answer this my colleagues have recently put together not merely four but six +'s."

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Donna Grant

"We are sometimes asked what the result would be if we put four +'s in one gene. To answer this my colleagues have recently put together not merely four but six +'s."

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Donna Grant

"It was inevitable that in doing this I should arrive at new results, and it is perhaps understandable that in the end I have felt impelled to present these results not only in the dry form of a catalogue, but also in a more connected and personal one."

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Donna Grant

"Our planet doesn't seem to be the result of anything very special."

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Donna Grant

"All great results in our universe are founded in motions and forces the most minute."

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Donna Grant

"My analysis was directed toward purely physical conditions, such as defective wiring, presence of lack of air spaces between metal flues and woodwork, etc., and the results were presented in these terms."

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Donna Grant

"Honestly achieved results surpass all others."

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Donna Grant

"I worked hard. Anyone who works as hard as I did can achieve the same results."

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Donna Grant

"I know I stand visibly onstage, but my function is still unseen, because I rarely see the immediate results of what I am saying or doing or writing."

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Donna Grant

"Everyone ought to bear patiently the results of his own conduct."

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Donna Grant

"The gratification comes in the doing, not in the results."

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Francis Crick
"For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the - class as having one too few."

Class

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Francis Crick
"A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement."

Agreement

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Francis Crick
"It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid."

May

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Francis Crick
"We are sometimes asked what the result would be if we put four +'s in one gene. To answer this my colleagues have recently put together not merely four but six +'s."

Result

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Francis Crick
"The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar."

Balance

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Francis Crick
"It now seems certain that the amino acid sequence of any protein is determined by the sequence of bases in some region of a particular nucleic acid molecule."

Now

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Francis Crick
"Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid."

Determination

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Francis Crick
"It seems likely that most if not all the genetic information in any organism is carried by nucleic acid - usually by DNA, although certain small viruses use RNA as their genetic material."

Information

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Francis Crick
"How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons."

Nothing

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Francis Crick
"If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place."

Example

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