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Derek Barton was a British chemist who won the Nobel Prize in Chemistry in 1969 for his work on the theory of chemical reactions and molecular structure. His contributions to the field of organic chemistry and his development of the concept of "conformational analysis" have been influential in advancing the understanding of chemical processes.
"X-Ray crystallography is nowadays an accurate and rapid method of determining conformation in the crystal lattice, which conformation usually corresponds to the preferred conformation in solution."
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"It does not seem, however, that organic chemists were much worried about barriers to rotation in organic molecules in general at that time because there was no technique available to demonstrate the phenomenon experimentally."
Time,
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