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Charles Nicole

"It did not seem likely that I was destined to undertake research on typhus."

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"It did not seem likely that I was destined to undertake research on typhus."

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Donna Grant

"I jealously guard my research time and I love fully immersing myself in those dusty old books and papers. It's one of the most enjoyable parts of my job."

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Personal Development

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Donna Grant

"Find as much information about your subject as you can."

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Donna Grant

"Archive material is a fabulous starting point - individual documents are like signposted roads, heading to a variety of intriguing possibilities."

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Donna Grant

"The biologically harmful effects of man-made environmental radiation was a jigsaw of existing information that needed to be assembled by a group of independent researchers that had a broad range of knowledge and were free of corrupt corporate government influence."

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Donna Grant

"I don't believe in writing anything that I don't know about or haven't researched about personally. I like to transport the reader to places, and in order to do that I have to do the research."

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Donna Grant

"They show that roughly two-thirds of a group of neurotic patients will recover or improve to a marked extent within about two years of the onset of their illness, whether they are treated by means of psychotherapy or not."

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Donna Grant

"A successful radiation researcher must research both radiation and the harmful biological effects of the radiation exposures received by the researcher."

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Donna Grant

"No data on air propellers was available, but we had always understood that it was not a difficult matter to secure an efficiency of 50% with marine propellers."

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Donna Grant

"The CIA's research program is described in a book called The Search for the Manchurian Candidate."

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Donna Grant

"There is more to folklore research than fieldwork. This is why in all of my other upper-division courses I require a term paper involving original research."

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Charles Nicole
"I was less successful in my attempts to effect preventive vaccination against typhus by using the virus and in trying to produce large quantities of serum using large animals."

Success

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Charles Nicole
"Just as the only reservoir for the typhus virus in nature is provided by man, so the only vector of infection is the louse. The bite of the louse is not virulent immediately after the infecting meal. It becomes so only towards the 7th day following infection."

Nature

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Charles Nicole
"At the time when I was conducting my research there was no known method for taking the guinea pig's temperature. I demonstrated a technique which is now widely used."

Time

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Charles Nicole
"Most of the doctors in the Tunisian administration, especially those in country districts, contracted typhus and approximately one third of them died of it."

Country

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Charles Nicole
"I demonstrated the characteristics of experimental fever. It appears after an incubation period which is never less than five days. It follows the same pattern as natural fever in man, but is of shorter duration and less pronounced."

Man

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Charles Nicole
"The discovery that I soon made that the guinea pig was also susceptible to infection made it possible for me, from the third year on, to preserve the virus on this animal."

Discovery

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Charles Nicole
"Of all the problems which were open to me for study, typhus was the most urgent and the most unexplored. We knew nothing of the way in which contagion spread."

Nothing

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Charles Nicole
"My first attempts to transmit typhus to laboratory animals, including the smaller species of monkeys, had failed, as had those of my predecessors, for reasons which I can easily supply today."

Animals

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Charles Nicole
"Even if it had not been possible to reproduce the disease in animals and consequently to verify the hypothesis, this simple observation would have been sufficient to demonstrate the way in which the disease was propagated."

Animals

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Charles Nicole
"From the practical point of view, the susceptibility to infection of the guinea pig proved to be the most useful step forward. Today, all laboratories use this animal for preserving the virus."

Today

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