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Charles Nicole

"I demonstrated the characteristics of experimental fever. It appears after an incubation period which is never less than five days. It follows the same pattern as natural fever in man, but is of shorter duration and less pronounced."

Man,
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"I demonstrated the characteristics of experimental fever. It appears after an incubation period which is never less than five days. It follows the same pattern as natural fever in man, but is of shorter duration and less pronounced."

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Akiroq Brost

"When a man is wrapped up in himself, he makes a pretty small package."

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Personal Development

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Akiroq Brost

"After coming into contact with a religious man I always feel I must wash my hands."

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Personal Development

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Akiroq Brost

"The ideas gained by men before they are twenty-five are practically the only ideas they shall have in their lives."

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Personal Development

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Akiroq Brost

"It is the child in man that is the source of his uniqueness and creativeness, and the playground is the optimal milieu for the unfolding of his capacities and talents."

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Personal Development

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Akiroq Brost

"All free men, wherever they may live, are citizens of Berlin. And therefore, as a free man, I take pride in the words "Ich bin ein Berliner!""

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Personal Development

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Akiroq Brost

"Most people know no other way of judging men's worth but by the vogue they are in, or the fortunes they have met with."

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Personal Development

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Akiroq Brost

"The historian must have some conception of how men who are not historians behave. Otherwise he will move in a world of the dead. He can only gain that conception through personal experience, and he can only use his personal experiences when he is a genius."

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Personal Development

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Akiroq Brost

"The mountains, the forest, and the sea, render men savage; they develop the fierce, but yet do not destroy the human."

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Personal Development

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Akiroq Brost

"A man in the house is worth two in the street."

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Personal Development

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Akiroq Brost

"In order for the artist to have a world to express he must first be situated in this world, oppressed or oppressing, resigned or rebellious, a man among men."

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Charles Nicole
"I demonstrated the characteristics of experimental fever. It appears after an incubation period which is never less than five days. It follows the same pattern as natural fever in man, but is of shorter duration and less pronounced."

Man

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Charles Nicole
"I was less successful in my attempts to effect preventive vaccination against typhus by using the virus and in trying to produce large quantities of serum using large animals."

Success

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Charles Nicole
"The fact that I was fortunate enough to escape contagion, in spite of frequent, sometimes daily contacts with the disease, was because I soon guessed how it spread."

Disease

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Charles Nicole
"My first attempts to transmit typhus to laboratory animals, including the smaller species of monkeys, had failed, as had those of my predecessors, for reasons which I can easily supply today."

Animals

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Charles Nicole
"Of all the problems which were open to me for study, typhus was the most urgent and the most unexplored. We knew nothing of the way in which contagion spread."

Nothing

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Charles Nicole
"The discovery that I soon made that the guinea pig was also susceptible to infection made it possible for me, from the third year on, to preserve the virus on this animal."

Discovery

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Charles Nicole
"At the time when I was conducting my research there was no known method for taking the guinea pig's temperature. I demonstrated a technique which is now widely used."

Time

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Charles Nicole
"It did not seem likely that I was destined to undertake research on typhus."

Research

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Charles Nicole
"Just as the only reservoir for the typhus virus in nature is provided by man, so the only vector of infection is the louse. The bite of the louse is not virulent immediately after the infecting meal. It becomes so only towards the 7th day following infection."

Nature

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Charles Nicole
"From the practical point of view, the susceptibility to infection of the guinea pig proved to be the most useful step forward. Today, all laboratories use this animal for preserving the virus."

Today

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