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Francis Crick

"How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons."

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"How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons."

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Donna Grant

"Nothing that you have not given away will ever be really yours."

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Donna Grant

"As it is the characteristic of great wits to say much in few words, so small wits seem to have the gift of speaking much and saying nothing."

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Donna Grant

"Since philosophy now criticizes everything it comes across, a critique of philosophy would be nothing less than a just reprisal."

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Donna Grant

"There is nothing so difficult to marry as a large nose."

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Donna Grant

"Even if you have nothing to write, write and say so."

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Donna Grant

"Nothing is so unbelievable that oratory cannot make it acceptable."

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Donna Grant

"Nothing like a little judicious levity."

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Donna Grant

"Nothing is easy to the unwilling."

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Donna Grant

"The world is all a carcass and vanity, The shadow of a shadow, a play And in one word, just nothing."

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Donna Grant

"Nothing is so firmly believed as what we least know."

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Francis Crick
"A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement."

Agreement

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Francis Crick
"It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid."

May

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Francis Crick
"The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar."

Balance

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Francis Crick
"It now seems certain that the amino acid sequence of any protein is determined by the sequence of bases in some region of a particular nucleic acid molecule."

Now

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Francis Crick
"Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid."

Determination

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Francis Crick
"It seems likely that most if not all the genetic information in any organism is carried by nucleic acid - usually by DNA, although certain small viruses use RNA as their genetic material."

Information

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Francis Crick
"How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons."

Nothing

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Francis Crick
"If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place."

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Francis Crick
"A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here."

Ideas

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Francis Crick
"It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code."

Nature

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