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"After realizing that we would eventually be able to build molecular machines that could arrange atoms to form virtually any pattern that we wanted, I saw that an awful lot of consequences followed from that."
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"We may say that a basic substance is one which has a lone pair of electrons which may be used to complete the stable group of another atom, and that an acid is one which can employ a lone pair from another molecule in completing the stable group of one of its own atoms."

"The emitters of the spectral series are without exception single atoms, not compounds of atoms."

"It is more likely that more than a century will pass before we know the structure of the chemical atoms as thoroughly as we do our solar system."

"For under certain conditions the chemical atoms emit light waves of a specific length or oscillation frequency - their familiar characteristic spectra - and these can come in the form of electromagnetic waves only from accelerated electric quanta."

"The mind of man has perplexed itself with many hard questions. Is space infinite, and in what sense? Is the material world infinite in extent, and are all places within that extent equally full of matter? Do atoms exist or is matter infinitely divisible?"
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"An international race in the relevant technologies is getting under way at this point, not necessarily with an understanding of where that race leads in the long run, but strongly motivated by the short-term payoffs."

"If you take all the factories in the world today, they could make all the parts necessary to build more factories like themselves. So, in a sense, we have a self-replicating industrial system today, but it would take a tremendous effort to copy what we already have."

"The really big difference is that what you make with a molecular machine can be completely precise, down to the tiniest degree of detail that can exist in the world."

"I had been impressed by the fact that biological systems were based on molecular machines and that we were learning to design and build these sorts of things."

"But while doing that I'd been following a variety of fields in science and technology, including the work in molecular biology, genetic engineering, and so forth."

"I've encountered a lot of people who sound like critics but very few who have substantive criticisms. There is a lot of skepticism, but it seems to be more a matter of inertia than it is of people having some real reason for thinking something else."

"But if we can manage it so people don't have things forced on them that they don't want, I think there's every reason to believe things can settle out in a situation that is recognizably better than the one we're stuck in today."

"Protein engineering is a technology of molecular machines - of molecular machines that are part of replicators - and so it comes from an area that already raises some of the issues that nanotechnology will raise."

"It's a lot easier to see, at least in some cases, what the long-term limits of the possible will be, because they depend on natural law. But it's much harder to see just what path we will follow in heading toward those limits."

"My work at MIT had focused on what we could build in space once we had inexpensive space transportation and industrial facilities in orbit. And this led to various sorts of work in space development."
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