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Charles Nicole

"From the practical point of view, the susceptibility to infection of the guinea pig proved to be the most useful step forward. Today, all laboratories use this animal for preserving the virus."

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"From the practical point of view, the susceptibility to infection of the guinea pig proved to be the most useful step forward. Today, all laboratories use this animal for preserving the virus."

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Akiroq Brost

"The sacred moment!"

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Personal Development

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Akiroq Brost

"The time is now. What you have to do, do it now."

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Akiroq Brost

"Today is a sacred moment."

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Personal Development

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Akiroq Brost

"The best of today lays a great foundation for tomorrow."

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Personal Development

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Akiroq Brost

"Write a daily gratitude."

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Akiroq Brost

"The gift of today, blessings of the moment."

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Akiroq Brost

"I always see things that I can improve. But frankly with Stripes, I'm surprised at how effective it is, even today, and how vibrant that movie is and how juicy the performances all are."

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Akiroq Brost

"Your sacred time is now! Begin to live passionately."

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Akiroq Brost

"My voice is stronger today than ever."

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Akiroq Brost

"Never let yesterday use up too much of today."

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Charles Nicole
"The fact that I was fortunate enough to escape contagion, in spite of frequent, sometimes daily contacts with the disease, was because I soon guessed how it spread."

Disease

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Charles Nicole
"My first attempts to transmit typhus to laboratory animals, including the smaller species of monkeys, had failed, as had those of my predecessors, for reasons which I can easily supply today."

Animals

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Charles Nicole
"The discovery that I soon made that the guinea pig was also susceptible to infection made it possible for me, from the third year on, to preserve the virus on this animal."

Discovery

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Charles Nicole
"It did not seem likely that I was destined to undertake research on typhus."

Research

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Charles Nicole
"Just as the only reservoir for the typhus virus in nature is provided by man, so the only vector of infection is the louse. The bite of the louse is not virulent immediately after the infecting meal. It becomes so only towards the 7th day following infection."

Nature

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Charles Nicole
"From the practical point of view, the susceptibility to infection of the guinea pig proved to be the most useful step forward. Today, all laboratories use this animal for preserving the virus."

Today

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Charles Nicole
"Even if it had not been possible to reproduce the disease in animals and consequently to verify the hypothesis, this simple observation would have been sufficient to demonstrate the way in which the disease was propagated."

Animals

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Charles Nicole
"Most of the doctors in the Tunisian administration, especially those in country districts, contracted typhus and approximately one third of them died of it."

Country

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Charles Nicole
"At the time when I was conducting my research there was no known method for taking the guinea pig's temperature. I demonstrated a technique which is now widely used."

Time

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Charles Nicole
"I was less successful in my attempts to effect preventive vaccination against typhus by using the virus and in trying to produce large quantities of serum using large animals."

Success

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